EUCAST http://www.eucast.org/ EUCAST en EUCAST http://www.eucast.org/main/typo3conf/ext/tt_news/ext_icon.gif http://www.eucast.org/ EUCAST TYPO3 - get.content.right http://blogs.law.harvard.edu/tech/rss Fri, 06 Sep 2019 14:16:39 +0200 EUCAST recruits PKPD experts Shampa Das and Joseph Meletiadis http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=335&cHash=59756771256d56652e399a42ff26fca7 In an open process EUCAST has recruited two PKPD experts, Shampa Das (UK) and Joseph Meletiadis... In an open process EUCAST has recruited two PKPD experts, Shampa Das (UK) and Joseph Meletiadis (Greece and NL) and thereby increased its competence in the field. 

Recognising the pivotal importance of pharmacokinetics and pharmacodynamics (PK/PD) in the process of setting clinical breakpoints, EUCAST recruited two PK/PD experts during the summer of 2019. Both will be members of the Steering Committee.

Dr Shampa Das is a Senior Lecturer at the Centre for Antimicrobial Pharmacodynamics and Therapeutics, University of Liverpool, UK. She has previously been employed as a Director of Clinical Pharmacology at the Antibiotics Unit, AstraZeneca. She has vast experience with drug development, preclinical PK/PD and clinical support to aid optimal dose selection, as well as extensive experience with the regulatory process.

Dr Joseph Meletiadis is an Associate Professor of Microbiology at the University of Athens, and Head of the Mycology Unit in Attikon General Hospital, Athens, Greece. He is also a research scientist in the Erasmus Medical Center, Rotterdam, The Netherlands. Dr Meletiadis is also the clinical data coordinator of the EUCAST Subcommittee for antifungal susceptibility testing (AFST) and a member of the executive committee of the ESCMID Study Group on PK/PD of anti-infectives. Joseph has extensive experience with in vitro and in vivo PK-PD modelling and MIC-testing in relation to the setting of clinical breakpoints.

We welcome Shampa and Joseph to the EUCAST Steering Committee!

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Fri, 06 Sep 2019 14:16:39 +0200
"Rationale for the reference method for MIC determination of M. tuberculosis" posted http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=334&cHash=3909181732276c9b190cf1c759357bb8 A new document "Rationale for the reference method for MIC determination of M.... Rationale for the reference method for MIC determination of M. tuberculosis" posted on website. ]]> Tue, 03 Sep 2019 16:16:50 +0200 Florfenicol RD from VetCAST http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=333&cHash=f4de1931f44e5e096beeb91f4df058f3 Florfenicol RD v 1.0 published by VetCAST now available. Florfenicol RD v 1.0 published by VetCAST now available.

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Fri, 16 Aug 2019 09:00:02 +0200
FAQ document update. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=332&cHash=de19471d7b496eba1efd56357b691aab FAQ document updated. New questions and answers on the new EUCAST definitions of S,I and R and on... FAQ document updated. New questions and answers on the new EUCAST definitions of S,I and R and on ATU.]]> Mon, 12 Aug 2019 13:00:57 +0200 B. pseudomallei breakpoints and methods - comments and response to consultation http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=331&cHash=bde3fcc04b776b0feaa9d186c0d30198 Following the consultation on proposed B.pseudomallei breakpoints, EUCAST publishes comments and... comments and response. A table listing breakpoints (intended for the 2020 EUCAST v 10 breakpoint table) is at the end of the document.]]> Tue, 23 Jul 2019 16:44:59 +0200 EUCAST consultation (comments and responses) on the implementation of "Susceptible, increased exposure" http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=330&cHash=1f62d25a7399e901e262a24b60e9ca66 The EUCAST consultation on the "Susceptible, increased exposre" resulted in several... Susceptible, increased exposre" resulted in several comments. These and EUCAST responses are now available. ]]> Mon, 22 Jul 2019 16:39:20 +0200 Antimycobacterial susceptibility testing http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=329&cHash=aab27f34210e7227a0c80afc00ec1b31 Several changes - rationale documents for bedaquiline and delaminide published, consultation... Several changes - rationale documents for bedaquiline and delaminide published, consultation finalised, and a reference method for MIC testing of Mycobacteria published.

See the web pages for Antimycobacterial susceptibility testing.

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Fri, 19 Jul 2019 11:52:26 +0200
EUCAST documents in Serbian on NAC website. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=328&cHash=30e38b2855d014a0b99c5723143ed22d All EUCAST documents have been translated to Serbian and are now available from the NAC website. translated to Serbian and are now available from the NAC website.]]> Fri, 05 Jul 2019 10:09:39 +0200 Revised expert rules published. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=327&cHash=e981d226ffefbe0f39f575b05ccd6bec All expert rules have been revised. Public consultation completed. All expert rules have been revised. Public consultation completed.

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Fri, 14 Jun 2019 09:40:32 +0200
Maps showing EUCAST implementation updated. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=326&cHash=e15a86aa05e6296b01a61b6052f3cd04 Maps showing the implementation of EUCAST have been updated for 2019. implementation of EUCAST have been updated for 2019.]]> Sat, 25 May 2019 12:24:32 +0200 EUCAST public consultation (until 30 June) on proposed breakpoints for Burkholderia pseudomallei http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=325&cHash=4d2563a2faabb5e61fd2b770f662dac7 EUCAST public consultation on proposed breakpoints for Burkholderia pseudomallei EUCAST public consultation on proposed breakpoints for Burkholderia pseudomallei

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Wed, 22 May 2019 23:20:06 +0200
Proposed joint CLSI/EUCAST SOP for optimizing disk contents. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=324&cHash=5fc350e56af8ad19681f749980b93901 A joint CLSI/EUCAST ad hoc subcommittee/working group has proposed an SOP for the determination of... A joint CLSI/EUCAST ad hoc subcommittee/working group has proposed an SOP for the determination of optimal disk contents. Comments are invited through either committee procedure. 

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Tue, 21 May 2019 16:09:05 +0200
Modified warning against the use of gradient tests for confirming vancomycin resistance in enterococci. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=323&cHash=3816a37d56a59e4cd24f70b62ad85c67 See Warnings page Warnings page]]> Tue, 21 May 2019 11:58:28 +0200 Consultation on Proposed revision of aminoglycoside breakpoints http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=322&cHash=47b22896ff2d66a3a4e077070f05c0a2 EUCAST proposes to revise aminoglycoside breakpoints - public consultation 30 May, 2019. EUCAST proposes to revise aminoglycoside breakpoints - public consultation 30 May, 2019.

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Fri, 17 May 2019 08:37:35 +0200
EUCAST hopes to add one more PK-PD expert to the Steering Committee. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=321&cHash=113c73fd8e543b9919752ce715db3692 Due to the increasing number of proposals of new antimicrobials requesting marketing authorisation... Due to the increasing number of proposals of new antimicrobials requesting marketing authorisation and the increasing pace of reviewing existing breakpoints, the EUCAST Steering Committee is seeking to expand its expertise in pharmacokinetics-pharmacodynamics as it relates to susceptibility testing and clinical breakpoint setting. We are looking for a colleague with expertise in PK-PD and a general understanding of clinical infection and antibacterial therapeutics. Interested colleagues should address this no later than 30 June, 2019.

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Thu, 16 May 2019 10:24:00 +0200
Reference method for the determination of MICs in Mycobacteria - Consultation http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=320&cHash=c7716cd11a951a1f9868afd802f0869f The EUCAST Subcommittee on Anti-Mycobacterial susceptibility testing proposes a broth microdilution... M. tuberculosis complex. The documents are open for general consultation 15 May - 26 June, 2019. ]]> Wed, 15 May 2019 13:36:49 +0200 General consultation on changing categorisation of some wild type distributions http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=319&cHash=4dd149a4f106886c265774a14570a376 EUCAST proposes that agents and species currently categorised as SusceptibleHE (SHE) are... EUCAST proposes that agents and species currently categorised as SusceptibleHE (SHE) are re-categorised as “Susceptible, increased exposure” (I)

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Thu, 09 May 2019 16:52:44 +0200
The working order between industry, EMA and EUCAST. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=318&cHash=86a25535c07daaffdd8155fdb5ff1e03 Updated document to describe the working order between pharmaceutical industry, EMA and EUCAST. he working order between pharmaceutical industry, EMA and EUCAST.]]> Sun, 05 May 2019 17:59:47 +0200 Rapid AST direct from blood cultures - criteria for Acinetobacter baumannii added http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=317&cHash=c769a85f0cbf6e246686822727608faa Rapid AST direct from blood cultures - criteria for Acinetobacter baumannii were added and also... Rapid AST direct from blood cultures - criteria for Acinetobacter baumannii were added and also criteria for screening for ESBL and carbapenemases for epidemiological and/or infection control purposes. ]]> Thu, 02 May 2019 14:29:16 +0200 VetCAST workshop, London, 2-4 June, 2019. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=316&cHash=000ba6c5b8c2516c98467ef8fbd8dccc As in previous years, the EUCAST subcommittee VetCAST arranges a workshop om methodology for...

As in previous years, the EUCAST subcommittee VetCAST arranges a workshop om methodology for setting clinical breakpoints for veterinary pathogens. This 2½ day workshop will take place from June 2nd-4th at the Royal Veterinary College in London. 

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Thu, 25 Apr 2019 08:37:24 +0200
EUCAST posters at ECCMID 2019 http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=315&cHash=e6e264b64eaf2249dbd116fc04eecfb5 EUCAST posters for ECCMID 2019 now available. EUCAST posters for ECCMID 2019 now available.]]> Wed, 10 Apr 2019 13:51:28 +0200 EUCAST AFST QC Table updated! http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=314&cHash=7bfe3b1378c3e56180fffa76d1f98189 There is a new version and update of the EUCAST AFST QC table! There is a new version and update of the EUCAST AFST QC table

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Thu, 04 Apr 2019 13:12:43 +0200
EUCAST at ECCMID 2019 http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=313&cHash=3cb4aa5fdb132c4f15076ab957a2949b This document lists a variety of EUCAST activities during ECCMID 2019 in Amsterdam. This document lists a variety of EUCAST activities during ECCMID 2019 in Amsterdam.

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Thu, 28 Mar 2019 07:52:12 +0100
Antibiotic disks from 9 manufacturers - variable quality http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=312&cHash=ce669aae2016773ffcd2b19cc0cf5005 The quality of antibiotic disks from 9 manufacturers was checked by EUCAST. Some manufacturers had... The quality of antibiotic disks from 9 manufacturers was checked by EUCAST.

Some manufacturers had serious quality issues and laboratories are urged to ascertain the quality of disks used for routine susceptibility testing. The evaluation is now available in CMI.

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Wed, 06 Mar 2019 09:10:36 +0100
RAST of Acinetobacter http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=311&cHash=2d4c1019e811aab59399d234e653ba9a EUCAST is currently working on including Acinetobacter baumannii among species with criteria for... Acinetobacter baumannii among species with criteria for rapid AST directly from positive blood culture bottles. The organisms grows well already after 4 and 6 hours and criteria for short incubation seem possible. Recommendations available before the end of May, 2019.]]> Mon, 25 Feb 2019 16:30:54 +0100 Tedizolid rationale document available http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=310&cHash=7f3b4f963a9e1d4c9c5fb2ab295e1374 The rationale document describing tedizolid characteristics is now available among rationale... rationale document describing tedizolid characteristics is now available among rationale documents. ]]> Mon, 25 Feb 2019 08:58:23 +0100 Expert Rules - public consultation! http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=309&cHash=9a6b05423fc8544c6fa166b274905af8 The revised EUCAST Expert Rules document is now open for public consultation. The revised EUCAST Expert Rules document is now open for public consultation.

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Tue, 19 Feb 2019 16:57:19 +0100
Disks with and without clavulanic acid for the confirmation of ESBL http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=308&cHash=831995c871fe141f961aa7d289162c2e EUCAST introduces new disks for the confirmation of the presence of ESBL in Enterobacterales. See... guidance document.]]> Tue, 12 Feb 2019 17:18:00 +0100 Cyprus has appointed a NAC http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=307&cHash=31747287830c06c966052c06526c94e6 Dr Christos Karagiannis was appointed by the government to lead the newly formed NAC in Cyprus. Mon, 11 Feb 2019 08:54:38 +0100 Video to explain the EUCAST 2019 modified definitions of S, I and R and the ATU. http://www.eucast.org/eucast_news/news_singleview/?tx_ttnews%5Btt_news%5D=306&cHash=736645d3a4123f383c4f70df5a18cb68 Video to explain the EUCAST 2019 modified definitions of S, I and R and the ATU. definitions of S, I and R and the ATU. ]]> Tue, 22 Jan 2019 15:31:01 +0100