MIC and zone distributions and ECOFFs

MIC distributions - curated distributions

MIC distributions and zone diameter distributions are added to the distribution database when available.
The consequence of this is that ECOFF values may be added, TECOFFs may reach ECOFF status, and on occasion ECOFFs will be revised.  

Currently all MIC distributions are reviewed in accordance with criteria in SOP 10.1. 


The order of review/revision is






















Currently the following list of agents are under review (2019 - 20):

  • ciprofloxacin
  • nalidixic acid
  • colistin
  • daptomycin
  • temocillin
  • gentamicin
  • tobramycin
  • amikacin
  • meropenem, imipenem, ertapenem and doripenem (but more data is incoming)
  • tigecycline 
  • florfenicol
  • fosfomycin
  • amoxicillin
  • amoxicillin-clavulanic acid