Clinical breakpoints

Clinical breakpoints

Breakpoint tables for bacteria

EUCAST instruction video on how to use the breakpoint table - download here

 

The changes between EUCAST Breakpoint Tables v 8.0 (1 Jan, 2018) and 8.1 (16 May, 2018) are highlighted in light blue in v 8.1. They are:

- Enterobacterales, carbapenems comment 1

- Staphylococcus spp, penicillins comment 4

- Dosing tab, standard dosing of colistin

 

The most important changes between EUCAST Breakpoint Tables v 7.1 and v 8.0 are marked in pale yellow (or as underlined text in footnotes) in the tables and are listed here:

- EUCAST recommendations for MIC determination added.

- Enterobacteriaceae breakpoints validated for Plesiomonas shigelloides (except for aminoglycosides)

- Clarification that broth microdilution is the only approved method for colistin MIC determination.

- Breakpoints for Aeromonas spp. added (tab Aeromonas)

- Ceftaroline breakpoints for S. aureus revised.

- Macrolide breakpoints for H. influenzae removed following consultation.

- Fluoroquinolone breakpoints for M. catarrhalis revised following consultation.

- Clarification on the use of PK-PD breakpoints added.

- Dosages table revised and information on special situations (indications and/or species) added.

- Changes are listed in detail in tab "Changes" in breakpoint tables.

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Breakpoints published in Addendum during the year will be part of the next version of the full Clinical breakpoint tables valid from early January each year.

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Note: To utilize all functions in the Excel® file, use Microsoft™ original programs only.

 

 

Breakpoint table for Candida spp and Aspergillus spp

 

 

The format for MIC dilutions have been changed: 0.03 to 0.032 mg/L, 0.06 to 0.064 mg/L and 0.12 to 0.125 mg/L..
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Breakpoints published in Addendum during the year will be part of the next version of the full Clinical breakpoint tables valid from early January each year.

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Previous versions of breakpoint tables

 

Previous versions of breakpoint tables. 

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Definitions of clinical breakpoints and epidemiological cut off values

Modified definitions valid from 1 January, 2019.

 

 

 

Last update: 07 April 2013