MIC distributions and ECOFFs
The website gives MIC distributions (and since 2010 inhibition zone diameter distributions generated with the new EUCAST disk diffusion method) for a wide range of organisms and antimicrobial agents, including antifungals.
The distributions are based on collated data from a total of more than 27000 MIC distributions containing more than several million MICs from worldwide sources. The distributions include MICs from national and international studies such as resistance surveillance programs (Alexander, BSAC, ECO-SENS, MYSTIC, NORM and SENTRY), as well as MIC distributions from published articles, the pharmaceutical industry, veterinary programmes and individual laboratories. Histograms display wild type organisms, together with EUCAST clinical breakpoints and epidemiological cut-off values (ECOFFs). The distributions should never be referred to in any epidemiological context since data from many time periods and many countries have been aggregated.
Contributions of MIC and/or Zone diameter distributions can be made using the following Excel file templates:
- MIC distributions organised by agent or species
- Zone diameter distributions organised by agent or species
The curators of the database are currently Gunnar Kahlmeter, Erika Matuschek, Jenny Åhman, Derek Brown and John Turnidge.