MIC and zone distributions and ECOFFs

ECOFF review and revision

ECOFFs are based on available MIC and disk diffusion zone diameter distributions.

 

As more data is generated there is a need to 

 

  1. add new ECOFFs and TECOFFs
  2. revise existing ECOFFs and TECOFFs
  3. remove ECOFFs/TECOFFs where data do not match criteria in SOP 10.2

 

Below is a list of all major changes in MIC and zone diameter distributions and ECOFFs from 2023 and onwards.

 

  • Dalbavancin MIC distributions added and ECOFFs recalculated, October 2024
  • All MIC distributions have been reviewed in accordance with criteria in SOP 10.2. Mostly this is by agent, but on occasion, by species, during 2022 and 2023
  • Zone diameter distributions and ECOFFs for Salmonella enterica were reviewed 2024 (April) and following the addition of major contributions from veterinary and food safety projects all ECCOFFs were recalculated using the new autonomous algorithm which calculates individual and mean ECOFFs for all distributions. With new and added data, some values change as the background material increases in robustness. During 2023.