Development of clinical breakpoints and ECOFFs

Guideline VetCAST PK analysis

Author: VetCAST
Date 06/04/18

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Guideline to collect, archive, handle and analyse pharmacokinetic data for VetCAST

The purpose of this Guideline document is to provide proposals to facilitate standardisation of the processes of collection, archiving and analysis of individual pharmacokinetic (PK) data by VetCAST.

Pharmacokinetic–pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial susceptibility testing in horses

Elodie A. Lallemand, Alain Bousquet-Mélou, Laura Chapuis, Jennifer Davis, Aude A. Ferran, Butch Kukanich, Taisuke Kuroda, Marlène Z. Lacroix, Yohei Minamijima, Lena Olsén, Ludovic Pelligand, Felipe Ramon Portugal, Béatrice B. Roques, Elizabeth M. Santschi, Katherine E. Wilson, Pierre-Louis Toutain

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