Reference Method

The EUCAST reference method for the Mycobacterium tuberculosis complex is broth microdilution in Middlebrook 7H9. See following documents for further information.

EUCAST reference protocol for MIC determination of anti-tuberculous agents against isolates of the Mycobacterium tuberculosis complex

Main document
Version 8.2, 29 January 2025

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Annexe document to EUCAST reference protocol for MIC determination of anti-tuberculous agents against isolates of the Mycobacterium tuberculosis complex

Version 8.2, 29 January 2025

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SOP for calibrating surrogate MIC methods for M. tuberculosis against the EUCAST reference MIC method

Version 1.0, 18 July 2019

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Rationale for defining a reference method for the determination of minimum inhibitory concentrations (MIC) of anti-tuberculous agents for Mycobacterium tuberculosis complex

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EUCAST-AMST reference method: Inoculum preparation

8 November 2022

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Anyone with an interest in antimicrobial agents in general and antimicrobial breakpoints in particular is invited to contact EUCAST, ESCMID or one of the National Breakpoint Committees. To contact EUCAST use the Contact form below. 

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