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General

Resistance Detection

Resistance Detection Successful treatment of infectious diseases relies on knowledge and understanding of when antimicrobial resistance is an expected phenotype of the organism, and when resistance to antimicrobial agents may develop. The following documents provide up-to-date advice on how to…

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Publications and presentations

Publications and presentations En Route towards European Clinical Breakpoints for Veterinary Antimicrobial Susceptibility Testing: A Position Paper Explaining the VetCAST Approach. P-L Toutain et al. Frontiers in Microbiology, December 2017. Go to publication Population pharmacokinetics of…

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MIC:Zone Diameter correlations

MIC:Zone Diameter correlations The EUCAST Disk Diffusion test was developed by EUCAST under the auspices of ESCMID and with the help of many laboratories. The help of these laboratories is gratefully acknowledged. Most are listed under the EUCAST laboratory network . The work started in 2009 and is…

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Document Archive

Document Archive SOPs SOP 1. Setting breakpoints for new antimicrobial agents Previous versions: v 1.4 (2 December 2021) ; v 1.3 (23 October 2019) ; v 1.2 (21 November 2016) ; v 1.1 (26 September 2010) SOP 2. Harmonising breakpoints for existing antimicrobial agents Previous versions: v 2.4 (2…

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Rapid AST directly from blood culture bottles

Rapid AST directly from blood culture bottles EUCAST has developed a method for rapid AST (reading at 4, 6 or 8h and since April 2022 also after 16-20 hours incubation) directly from positive blood culture bottles (RAST). The rationale is available in JAC . Following the initial development,…

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National AST Committees (NAC)

National AST Committees (NAC) EUCAST recommends that countries form a “National Antimicrobial Susceptibility Testing Committee” (or a committee corresponding to this description). Developing a NAC in a Country can be useful when adopting or implementing EUCAST antimicrobial susceptibility testing…

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EUCAST - Home

The European Committee on Antimicrobial Susceptibility Testing - EUCAST EUCAST is a scientific committee formed in 1997 and is jointly organized by ESCMID , ECDC and European national breakpoint committees. EUCAST develops antimicrobial susceptibility testing methodology, interpretative criteria and…

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Development of clinical breakpoints and ECOFFs

Development of clinical breakpoints and ECOFFs How to collect and handle PK data Supporting information Guideline VetCAST PK analysis Author: VetCAST Date 06/04/18 Download PDF Guideline to collect, archive, handle and analyse pharmacokinetic data for VetCAST The purpose of this Guideline document…

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Education

Education Stay informed on EUCASTs upcoming and previous educational activities here. If you have any feedback or ideas, please contact us via the contact form in the bottom of the page. Upcoming Activites Upcoming activities (e.g. webinars) can be found here. Previous Activities Previous…

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Rationale Documents

Rationale Documents EUCAST rationale documents summarise the information on which the EUCAST clinical breakpoints are based. Bedaquiline Rationale for EUCAST clinical breakpoints Version 1.3, 4 July 2019 Download PDF Bedaquiline (TMC207) is a diarylquinoline, a new class of anti-tuberculosis (TB)…

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