Expert Rules EUCAST expert rules (listed below) are a tabulated collection of expert knowledge on interpretive rules. These rules should be applied to antimicrobial susceptibility testing to rationalise testing, reduce errors, and make appropriate recommendations for reporting particular…
Get to know moreGuidance Documents All Antibiotic Infection Methodology Pathogen Regulatory Document Title Date of Publication Previous Versions and Notes Infective endocarditis - EUCAST guidance on the reporting of antimicrobial susceptibility testing results July 2025 December 2024 Daptomycin in endocarditis and…
Get to know moreMIC Determination of non-fastidious and fastidious organisms The EUCAST recommendations for MIC determination for non-fastidious organisms are in complete agreement with the recommendations from the International Standards Organisation ( ISO ). For fastidious organisms (streptococci including S.…
Get to know moreClinical Breakpoint Tables Breakpoints are part of a system for categorizing microorganisms as: Susceptible (S) Susceptible, increased exposure (I) Resistant (R) To antimicrobial agents approved for use in the treatment of infectious diseases. Information of the structure of the tables and how they…
Get to know moreThe European Committee on Antimicrobial Susceptibility Testing - EUCAST EUCAST is a scientific committee formed in 1997 and is jointly organized by ESCMID , ECDC and European national breakpoint committees. EUCAST develops antimicrobial susceptibility testing methodology, interpretative criteria and…
Get to know moreBacteria Most of EUCAST’s work is dedicated to defining breakpoints for bacteria that cause infections in humans. How to Use This Section: This page gives you access to information and services related to pathogenic bacteria. Important: All resources here are complementary. Please review them…
Get to know moreInformation for pharmaceutical companies intending to bring new antimicrobial drugs to EUCAST for breakpoints The development of clinical breakpoints for new agents requires agreement and acceptance of the data generated in support of decisions on clinical breakpoints, wild type MIC distributions,…
Get to know moreWhen there are no breakpoints? When there are no breakpoints? Guidance document, 29 September 2024 Download PDF Sometimes breakpoints for a species and/or an agent are lacking in EUCAST tables. This may happen because data to allow setting breakpoints is lacking, especially for rare species;…
Get to know moreDisk Diffusion and Quality Control EUCAST have developed standardised disk diffusion methods for both aerobic and anaerobic bacteria. EUCAST antimicrobial susceptibility testing is performed with phenotypic methods, reference broth microdilution or standardised disk diffusion. The basis of all…
Get to know moreResistance Detection Successful treatment of infectious diseases relies on knowledge and understanding of when antimicrobial resistance is an expected phenotype of the organism, and when resistance to antimicrobial agents may develop. The following documents provide up-to-date advice on how to…
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