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General

Rationale Documents

Rationale Documents Rationale documents pertaining to breakpoints determined by the EUCAST Veterinary Subcommittee. Florfenicol (Cattle) Rationale for EUCAST clinical breakpoints, version 1.0 10 August 2019 Download PDF Amoxicillin-Clavulanic Acid (AMC) Dog: oral and iv administration (VetCAST)…

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Rationale Documents

Rationale Documents The EUCAST Rationale Documents currently available are listed below. Rationale documents for antifungal agents are listed elsewhere, see " Antifungal rationale documents ". A template for companies aiming to create a comprehensive rationale document for new agents or for existing…

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Sitemap

Sitemap EUCAST - Home About EUCAST Organisation Steering Committee General Committee EUCAST Statutes National AST Committees (NAC) Network Laboratories Development Laboratories (EDL) Subcommittees Antimycobacterial Susceptibility Testing (AMST) Antifungal Susceptibility Testing (AFST) Veterinary…

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Development of clinical breakpoints and ECOFFs

Development of clinical breakpoints and ECOFFs As with other breakpoints for antimicrobials the background for EUCAST breakpoints are given in Rationale Documents. Since for antifungals specific technical issues in testing may exist, technical notes are developed if needed. As with the general…

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Development of Clinical Breakpoints and ECOFFs

Development of Clinical Breakpoints and ECOFFs These pages collate information on the definition of clinical breakpoints and the process of setting MIC breakpoints. Background information is given in the Rationale Documents and in Public Consultations and the MIC:ZD (MIC vs. zone diameter)…

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Rationale documents

Rationale documents Amphotericin B v 3.0 (26 June 2025) Anidulafungin vs. Candida v 5.0 (26 June 2025) Caspofungin vs Candida - there is no caspofungin RD and no specific caspofungin breakpoints. Use anidulafungin and micafungin as markers for caspofungin susceptibility where isolates "S" to both…

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Rationale Documents

Rationale Documents EUCAST rationale documents summarise the information on which the EUCAST clinical breakpoints are based. Bedaquiline Rationale for EUCAST clinical breakpoints Version 1.3, 4 July 2019 Download PDF Bedaquiline (TMC207) is a diarylquinoline, a new class of anti-tuberculosis (TB)…

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VetCAST

Veterinary Committee on Antimicrobial Susceptibility Testing (VetCAST) VetCAST is a EUCAST subcommittee dealing with all aspects of antimicrobial susceptibility testing of bacterial pathogens of animal origin and animal bacteria with zoonotic potential. Subcommittee Discover More Development of…

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Development of Clinical Breakpoints and ECOFFs

Development of Clinical Breakpoints and ECOFFs The EUCAST AMST develops breakpoints and methods for antimicrobial susceptibility testing of mycobacteria. Rationale Documents Discover More Public Consultations A chance to review proposed EUCAST changes. Discover More Submit non-truncated MIC…

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Development of clinical breakpoints and ECOFFs

Development of clinical breakpoints and ECOFFs How to collect and handle PK data Supporting information Guideline VetCAST PK analysis Author: VetCAST Date 06/04/18 Download PDF Guideline to collect, archive, handle and analyse pharmacokinetic data for VetCAST The purpose of this Guideline document…

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