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General

Candida auris - comments to consultation and EUCAST AFST responses and actions

EUCAST AFST recently proposed new breakpoints for amphotericin B, three echinocandins and flucytosine against Candida auris . A public consultation was held 2025-03-06 - 2025-04-17. Now (2025-06-17) the EUCAST AFST has responded to comments .

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Invitation to EUCAST general updates via zoom

This is a general invitation to attend EUCAST zoom updates on the 11th of November (8 AM, 1 PM and 4 PM). Current EUCAST projects will be described, the next breakpoint table summarised and there will be opportunities to discuss.

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RAST breakpoints for prolonged incubation (16-20h) now published in JAC

Recently we made breakpoints available (on the website) for RAST incubation beyond the standard 4, 6 and 8h for when reading at those incubation times is not prectical. Now the rationale for this is published in the Journal of Antimicrobial Chemotherapy .

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All MIC/Zone diameter calibration file updated. Anaerobic bacteria added.

With changes in the breakpoint table v 12.0 and the adding of disk diffusion criteria for anaerobic bacterial and for Vibrio spp, the calibration filesshowing the relationship between MIC and inhibition zone diameters ​​​​​​​ need updating. These are now available (Vibrio spp to follow).

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Expert rules, Staphylococcus spp updated

The Staphylococcus spp. Expert Rules document was updated 1 Febr, 2023. The detection of benzylpenicillin resistance in S. lugdunensis is based on the breakpoints only - the assessment of inhibition zome edge has been removed fro S. lugdunensis but remains for S. aureus .

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Antimycobacterial Susceptibility Testing (AMST)

Subcommittee on Antimycobacterial Susceptibility Testing (AMST) In November 2014, a workshop in Basel brought together representatives from the EUCAST Steering Committee, the ESCMID Study Group for Mycobacterial Infections (ESGMYC), and the European Medicines Agency (EMA) to discuss data…

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News from VetCAST - publication on PK/PD for benzylpenicillin in horses

Pharmacokinetic–pharmacodynamic cutoff values for benzylpenicillin in horses to support the establishment of clinical breakpoints for benzylpenicillin antimicrobial susceptibility testing in horses. E.Lallemande et al, October, 2023.Front. Microbiol., 25 October 2023.Volume 14 - 2023 |…

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Public consultation on Endocarditis breakpoints - EUCAST response

Following public consultation, EUCAST publishes formal responses to queries and views submitted during the consultation period. The comments during the consultation on EUCAST proposed endocarditis breakpoints , the EUCAST responses and decisions are now published (20 November, 2024). Throughout the…

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EUCAST public consultation on breakpoints for intravenous use of fosfomycin.

EUCAST public consultation on breakpoints for intravenous use of fosfomycin . Consultation period 12 July - 12 September, 2023. The proposal has been revised following comments to the previous consultation and discussions with the EUCAST Steering Committee and stakeholders. Do not iterate comments…

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Temocillin MIC vs. inhibition zone diameters

MIC and zone diameter data on temocillin added to the Enterobacterales calibration/validation file (28 February, 2022). For anyone using EUCAST disk diffusion AST criteria, the calibration/validation files will provide valuable information and allow laboratories to benchmark local efforts with files…

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