Rapid AST in blood culture For selection of an efficacious antibiotic therapy rapid susceptibility results are desirable, but the usual overnight incubation precludes rapid results. EUCAST RAST fills this gap by providing results within 4 to 8 hours of incubation. The method is validated for…
Get to know moreRationale Documents The EUCAST Rationale Documents currently available are listed below. Rationale documents for antifungal agents are listed elsewhere, see " Antifungal rationale documents ". A template for companies aiming to create a comprehensive rationale document for new agents or for existing…
Get to know morePublications and Presentations 2025 2023 2022 2020 Archive The Mycobacterium tuberculosis complex based on the EUCAST reference protocol. Mansjö M, Espinosa-Gongora C, Samanci I, Groenheit R, Werngren J. Antimicrob Agents Chemother. 2025 Feb 13;69(2):e0094624. doi: 10.1128/aac.00946-24. Epub 2024…
Get to know moreEUCAST guidance on how to determine MIC values and develop distributions (and zone diameter distributions) for new agents in preparation for EUCAST and EMA evaluation. The development of new agents requires agreement and acceptance of the data generated in support of decisions on clinical…
Get to know moreGeneral Committee Meetings The EUCAST yearly General Committee meetings are open meetings, held during yearly ESCMID-Global conferences. Everyone interested in breakpoints and AST methods are welcome. Meeting minutes EUCAST General Committee meeting 2025 (ESCMID, Vienna) EUCAST General Committee…
Get to know moreThis is to clarify how "susceptibility (S and I)" and "resistance (R)" should be reported in AMR surveillance with the EUCAST definitions of S I and R . With the EUCAST definitions, the tradition to report "non-susceptibility" as the joint rate of %I and %R is abandoned. Previously (pre-2019) it was…
Get to know moreResistance Detection in RAST Some resistance mechanisms require other than clinical breakpoints for sensitive detection. EUCAST has validated using separate screening cut-offs for the detection of E. coli and K. pneumoniae with ESBL or carbapenemases. Screening for resistance mechanisms using RAST…
Get to know moreSusceptibility testing of fastidious organisms - is there an alternative to MH-F ? Public consultation 2025-06-19 - 08-29. The EUCAST medium MH-F was developed for AST of fastidious organisms.Colleagues in some areas of the world have difficulties obtaining the MH-F plate based on horse blood. The…
Get to know moreEUCAST Steering Committee The ESCMID-appointed Steering Committee consists of the Chair, Scientific Secretary, Clinical Data Co-ordinator, Technical Data Co-ordinator, Head of the EUCAST Development Laboratory, Educational Officer, Webmaster, Pharmacokinetic/Pharmacodynamic experts, a representative…
Get to know moreThe manufacturer of antimicrobial susceptibility testing material is responsible for the quality of the material provided to microbiological laboratories. The laboratory is responsible for the result provided to doctors and patients. To perform AST where there is intrinsic resistance is wasting the…
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