Bacteria Most of EUCAST’s work is dedicated to defining breakpoints for bacteria that cause infections in humans. How to Use This Section: This page gives you access to information and services related to pathogenic bacteria. Important: All resources here are complementary. Please review them…
Get to know moreWithin days the EUCAST website will have a new face. Do not worry - you do not have to prepare, change or add anything. The old webmaster bows out and someone new takes over. I have looked after the website and its transitions for exactly 25 years but have no hand in the most recent transition. I am…
Get to know moreFollowing frequent questions and pleas for further guidance, EUCAST has revised the document " What to do when there are no breakpoints ". This is not the type of document where a consultation is part of the process. However, it is important that colleagues understand and agree with the advice…
Get to know moreEUCAST introduced breakpoints in brackets in 2020. In breakpoint table 12.0 (2022) there are breakpoints in brackets for aminoglycosides, colistin and for clindamycin for Bacteroides spp. A guidance document describes how to interpret and report breakpoints in brackets.
Get to know moreInformation for pharmaceutical companies intending to bring new antimicrobial drugs to EUCAST for breakpoints The development of clinical breakpoints for new agents requires agreement and acceptance of the data generated in support of decisions on clinical breakpoints, wild type MIC distributions,…
Get to know moreWhat to do when there are no breakpoints? Not every agent and/or species have breakpoints in EUCAST breakpoint tables. For some there may be PK/PD breakpoints, for others MIC distributions to guide recommendations. In this guidance document EUCAST gives advice on how to deal with uncommon species or…
Get to know moreWhen there are no breakpoints? When there are no breakpoints? Guidance document, 29 September 2024 Download PDF Sometimes breakpoints for a species and/or an agent are lacking in EUCAST tables. This may happen because data to allow setting breakpoints is lacking, especially for rare species;…
Get to know moreDisk Diffusion and Quality Control EUCAST have developed standardised disk diffusion methods for both aerobic and anaerobic bacteria. EUCAST antimicrobial susceptibility testing is performed with phenotypic methods, reference broth microdilution or standardised disk diffusion. The basis of all…
Get to know moreResistance Detection Successful treatment of infectious diseases relies on knowledge and understanding of when antimicrobial resistance is an expected phenotype of the organism, and when resistance to antimicrobial agents may develop. The following documents provide up-to-date advice on how to…
Get to know moreThe EUCAST guidance document on susceptibility testing on L.pneumophila isupdated. Acquired antimicrobial resistance in L. pneumophila is rare [1-6]. However, a clinical isolate resistant to ciprofloxacin due to a single point mutation in the gyrA gene has been reported [7] and fluoroquinolone…
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