The guidance document on " What to do when there are no breakpoints " has been updated with recommendations for cefiderocol.
Get to know moreInformation for pharmaceutical companies intending to bring new antimicrobial drugs to EUCAST for breakpoints The development of clinical breakpoints for new agents requires agreement and acceptance of the data generated in support of decisions on clinical breakpoints, wild type MIC distributions,…
Get to know moreFollowing frequent questions and pleas for further guidance, EUCAST has revised the document " What to do when there are no breakpoints ". This is not the type of document where a consultation is part of the process. However, it is important that colleagues understand and agree with the advice…
Get to know moreEUCAST introduced breakpoints in brackets in 2020. In breakpoint table 12.0 (2022) there are breakpoints in brackets for aminoglycosides, colistin and for clindamycin for Bacteroides spp. A guidance document describes how to interpret and report breakpoints in brackets.
Get to know moreThe European Committee on Antimicrobial Susceptibility Testing - EUCAST EUCAST is a scientific committee formed in 1997 and is jointly organized by ESCMID , ECDC and European national breakpoint committees. EUCAST develops antimicrobial susceptibility testing methodology, interpretative criteria and…
Get to know moreWhat to do when there are no breakpoints? Not every agent and/or species have breakpoints in EUCAST breakpoint tables. For some there may be PK/PD breakpoints, for others MIC distributions to guide recommendations. In this guidance document EUCAST gives advice on how to deal with uncommon species or…
Get to know moreDisk Diffusion and Quality Control EUCAST have developed standardised disk diffusion methods for both aerobic and anaerobic bacteria. EUCAST antimicrobial susceptibility testing is performed with phenotypic methods, reference broth microdilution or standardised disk diffusion. The basis of all…
Get to know moreWhen there are no breakpoints? When there are no breakpoints? Guidance document, 29 September 2024 Download PDF Sometimes breakpoints for a species and/or an agent are lacking in EUCAST tables. This may happen because data to allow setting breakpoints is lacking, especially for rare species;…
Get to know moreResistance Detection Successful treatment of infectious diseases relies on knowledge and understanding of when antimicrobial resistance is an expected phenotype of the organism, and when resistance to antimicrobial agents may develop. The following documents provide up-to-date advice on how to…
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