What to do when there are no breakpoints? Not every agent and/or species have breakpoints in EUCAST breakpoint tables. For some there may be PK/PD breakpoints, for others MIC distributions to guide recommendations. In this guidance document EUCAST gives advice on how to deal with uncommon species or…
Get to know moreThe EUCAST breakpoint tables are part of a system for categorising microorganisms as susceptible (S and I) and resistant (R) to agents approved for use in the treatment of infectious diseases. Breakpoint tables are freely available but we would like to remind users of other parts of the system which…
Get to know moreEUCAST general and public consultation on breakpoints for anaerobic bacteria. Theconsultation pertains to the clinical breakpoints for Bacteroides spp., Prevotella spp., Fusobacterium necrophorum, Clostridium perfringens and Cutibacterium acnes that have now been reviewed against the MIC and zone…
Get to know moreFungi (AFST) The EUCAST AFST develops breakpoints and methods for antimicrobial susceptibility testing of fungi. Clinical breakpoints for fungi are listed in a separate document and are not included into the breakpoint table for bacteria. For MIC distributions for fungi, go to the EUCAST MIC…
Get to know moreAztreonam-avibactam has now obtained regulatory approval and breakpoints from EMA and EUCAST for Enterobacterales. These are S≤4, R>4 mg/L.Disk diffusion criteria and QC targets and ranges will be published shortly. There are no breakpoints for other species. Cefepime-enmtazobactam has now obtained…
Get to know moreBreakpoints in brackets in EUCAST tables EUCAST breakpoints in brackets Guidance document, 1 December, 2021 Download PDF Recently, EUCAST introduced the concept of “breakpoints in brackets” to warn against the use of specific agents without the use of additional therapeutic measures. For these…
Get to know moreEUCAST posted a general consultation on revised breakpoints for intravenous fosfomycin. Consultation period 14 May - 15 June, 2022. Revised breakpoints will be published in breakpoint table 2023.
Get to know moreGuidance Documents All Antibiotic Infection Methodology Pathogen Regulatory Document Title Date of Publication Previous Versions and Notes Infective endocarditis - EUCAST guidance on the reporting of antimicrobial susceptibility testing results November 2025 July 2025 December 2024 Daptomycin in…
Get to know moreAminopenicillin breakpoints were revised in the breakpoint table 13.0 (2023). EUCAST has been asked to provide guidance on how to implement the revised breakpoints in laboratory practice and systems .
Get to know moreProposed revision of breakpoints for trimethoprim-sulfamethoxazole and trimethoprim - public consultation 2025-05-07 - 2025-06-18. The current breakpoints of trimethoprim-sulfamethoxazole are higher than the epidemiological cut-off values for several species. There is absence of PK/PD data for…
Get to know more