Development of clinical breakpoints and ECOFFs As with other breakpoints for antimicrobials the background for EUCAST breakpoints are given in Rationale Documents. Since for antifungals specific technical issues in testing may exist, technical notes are developed if needed. As with the general…
Get to know moreGuidance Documents All Antibiotic Infection Methodology Pathogen Regulatory Document Title Date of Publication Previous Versions and Notes Infective endocarditis - EUCAST guidance on the reporting of antimicrobial susceptibility testing results November 2025 July 2025 December 2024 Daptomycin to…
Get to know moreThe following ECOFFs and breakpoints for antifungal agents have been established or revised and are now found in the associated revised rationale documents, the breakpoint document and the ECOFF and breakpoints document available at the EUCAST website: Download PDF
Get to know moreThere is only little news from EUCAST January 2021. The next EUCAST Steering Committee meeting is on February 1 - 3. Again via video links. Several users of EUCAST breakpoint tables have asked how to translate dosages (Tab Dosage) based on adult administration to pediatric clinical situations -…
Get to know moreGuidance Documents Guidance on how to qualify in-house performance of commercial tests for antifungal susceptibility testing before adoption of EUCAST breakpoints 16 April 2026 Download PDF Guidance on Interpretation of MICs for rare yeast without breakpoints in breakpoint tables 19 June 2024…
Get to know moreIn 2019, EUCAST abandoned the previously used definitions of S, I and R, and introduced categories S (Susceptible, standard dose), I (Susceptible, increased exposure) and R (Resistant). All breakpoints, dosages and modes of administration were reviewed and revised to match the changed definitions.…
Get to know morePublic consultation Public consultation is part of the EUCAST decision process. The consultation period is 4 - 12 weeks, and the dates of the beginning and end of the period is clearly stated. Previous public consultations with comments and EUCAST responses 2025 Archive Proposed new breakpoints for…
Get to know moreThe breakpoint table v 13.0 (2023) is under preparation (release for consultation 5 December, 2022). As part of this table, there are specific breakpoints for Corynebacterium diphtheriae and C. ulcerans. EUCAST has been requested to make these available as soon as possible. The now published table…
Get to know moreFluroquinolone breakpoints are under review and will likely be lowered for Enterobacterales whereas breakpoints for other species are less likely to change. Laboratories and manufacturers of susceptibility testing devices are adviced to take this under consideration and to be prepared to cope with…
Get to know moreThere are several public consultations which will expire 15 November, 2021. Vibrio species - genral consultationon EUCAST clinical breakpoints for five species pathogenic to man(1 October - 15 November). Queries on the material can be addressed to G Kahlmeter (gunnar.kahlmeter@eucast.org)…
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