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General

Phenotypic screening tests to detect resistance of clinical importance.

Phenotypic screening tests to detect resistance of clinical importance . In EUCAST breakpoint tables several breakpoints are listed as "Screening only". This document presents all of these and the actions proposed by EUCAST.

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Pefloxacin screening for fluoroquinolone resistance in Enterobacterales

Fluoroquinolone breakpoints are under review. Shortly there will be a public consultation. Since industry and users sometimes complain that EUCAST fails to warn of upcoming changes we now emphasize that (a) a change is coming, (b) breakpoints will be reduced further and that (c) screening for…

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RAST - breakpoints for additional agents now available!

Breakpoints for several additional agents have been added to the RAST breakpoint table and QC table . All development data has been made available, also for new agents. Visit the RAST website for more information.

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Updated RAST tables

There are a few changes to the RAST (rapid AST directly from positive blood culture bottles) breakpoint tables as a result of changes to the EUCAST regular breakpoint tables. An updated version of the RAST tables is published.

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Breakpoint table v 11.0 (2021) posted for consultation 4 Dec.

We are currently preparing the Breakpoint table v 11.0 (2021) for consultation 4 Dec - 18 Dec. A link will be available before the end of the day on "the Consultation" page and on the " Breakpoint table page" .

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What to do when there are no breakpoints - revised!

The EUCAST guidance on what to do when there are no breakpoints in the breakpoint table (species lacking, agent lacking, IE, dash etc) has been thoroughly revised in February 2024. Go to the EUCAST webpage for this and other Guidance documents .

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Guidance on the reporting of susceptibility in endocarditis pathogens

With the 2025 (v 15.0) breakpoint table (for formal release on the 1st of January) EUCAST has released guidance on the reporting of susceptibility test results on endocarditis pathogens to help explain how to use the breakpoints developed for endocarditis.

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Disk Diffusion and Quality Control

Disk Diffusion and Quality Control EUCAST have developed standardised disk diffusion methods for both aerobic and anaerobic bacteria. EUCAST antimicrobial susceptibility testing is performed with phenotypic methods, reference broth microdilution or standardised disk diffusion. The basis of all…

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The table listing breakpoints and ECOFFs for antifungal agents and relevant fungi is now updated.

Antifungal agents have MIC distributions in the EUCAST MIC distribution database. ECOFFs are assessed and revised as new data is available. Also clinical breakpoints are regularly assessed and sometimed revised. The EUCAST AFST subcommittee posts a table comparing breakpoints and available ECOFFs…

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EUCAST to review carbapenem breakpoints

EUCAST aims to review breakpoints for carbapenems, alone and in combination with inhibitors. Anyone with data to support a breakpoint process are invited to highlight and submit relevant evidence. At the end of the EUCAST process, we will invite colleagues to participate in the consultation process…

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