25 Feb 2021

Cefiderocol MIC and zone diameter correlates available.

The EUCAST MIC and zone diameter correlates for cefiderocol are now available. The isolates used for the analysis were selected to be difficult and there are isolates with many different resistance mechanisms. Disk diffusion provides results which can reliably be reproduced as belonging to the wild type and to the non-wild type part of the population with high MICs to cefiderocol. Providing a wider than usual ATU (Area of Technical Uncertainty) is to increase the robustness of disk diffusion, but also because MIC-testing is not necessarily straightforward, and the poorer correlation between MIC and zone diameter in this area is not necessarily a result of a failed disk test.

If you have questions on cefiderocol AST, please email the EUCAST Development Laboratory.